This kit uses RT-PCR to detect echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene in plasma or formalin-fixed paraffin-embedded tissue (FFPE). Test results may serve as a reference for clinical evaluation of defined EML4-ALK fusion gene in non-small-cell lung cancer (NSCLC) patients. Confirmed mutation: recommended medications include crizotinib, ceritinib, alectinib, etc.
Based on high-efficiency enzymatic processing technology, the test uses specific gene sequences as PCR targets. Human genomic sequence is used as internal quality control.
