This kit uses RT-PCR to detect v-raf murine sarcoma viral oncogene homolog B1 (BRAF) gene mutations in plasma or formalin-fixed paraffin-embedded tissue (FFPE) samples. Test results may serve as a reference for clincial evaluation of defined BRAF gene mutations in melanoma and non-small-cell lung cancer (NSCLC) patients. Confirmed mutation: recommended medications include dabrafenib, vemurafenib, trametinib, etc.
Based on high-efficiency enzymatic processing technology, the test uses specific gene sequences as PCR targets. Human genomic sequence is used as internal quality control.
