This kit uses RT-PCR to detect kirsten rat sarcoma viral oncogene (KRAS) gene mutations in formalin-fixed paraffin-embedded tissue (FFPE). Test results may serve as a reference for clinical evaluation of defined KRAS gene mutation in non-small cell lung cancer (NSCLC) and colorectal cancer patients. Confirmed mutation: the patient is not suitable to use cetuximab or panitumumab.
The test uses specific gene sequences as PCR target regions. Human genomic sequence is used as internal quality control.
